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In addition, pegilodecakin, a long-acting recombinant pegylated IL-10, has been evaluated in dose escalation/expansion study in patients with advanced solid tumors as a monotherapy or combination with other anticancer drugs in a phase I trial (NCT02009449)
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Addressing only one component produces incomplete results: healing tissue without resolving inflammation leads to re-injury, while suppressing inflammation without repairing tissue leaves the barrier compromised
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