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How does the blood-brain barrier work? - Darwin Microfluidics

Determination of midpoint potentials of roGFP variants Both roGFP2-iL and GRX-roGFP2-iL (1 μM final concentration) were allowed to equilibrate (2–3 h) with lipoic acid buffers [reduced form dihydrolipoic acid (DHLA)

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In addition to the PERK-ATF4-CHOP axis, other key ER stress pathways, such as IRE1/XBP1 and ATF6 also contribute to the UPR, collectively managing protein misfolding and restoring homeostasis, or, if stress persists, trigger cell death (Tabas and Ron, 2011)