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It is perhaps interesting to note, given the association of paracetamol induced drug-induced liver injury (DILI) hepatotoxicity and mitochondrial toxicity18,19 that CYP2E1 is located not only in the endoplasmic reticulum but also within mitochondria

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GERD protocols typically begin at the lower end, with 0.25 mg (250 mcg) representing a common starting point