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For example, rapid-acting antidepressants like ketamine produce lasting antidepressant effects by quickly reversing stress-induced synaptic atrophy and strengthening synaptic connections, while glutamatergic modulators (affecting NMDA-type receptors) are under investigation to boost homosynaptic plasticity and improve cognitive function in schizophrenia

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If tiredness is caused by a confirmed vitamin B12 deficiency, many people report noticing changes within: A few days to one week – some individuals feel improvement in energy levels relatively quickly

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