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Higher-dose oral B12 (e.g., 1000 µg daily) is sometimes used but should only be considered under clinical supervision with appropriate monitoring, particularly in cases of malabsorption where intramuscular treatment remains the first-line approach in UK practice

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[DOI] [PMC free article] [PubMed] [Google Scholar] 85.Wu F., Tian F.J., Lin Y., Xu W.M