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Long-term follow-up studies are needed to assess durability of therapeutic effects and to identify any delayed adverse effects or complications that might not be apparent in shorter-term investigations

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Finasteride, a 5-alpha reductase inhibitor that reduces DHT production, addresses the hormonal component of androgenetic alopecia but carries a well-documented profile of systemic side effects including sexual dysfunction, mood disturbance, and — in a subset of patients — persistent post-treatment syndrome