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NAFLD has become increasingly prevalent in the UK, affecting approximately one in three adults in its early stages, often associated with obesity, type 2 diabetes, and metabolic syndrome

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The IC metric quantifies observed-to-expected reporting discrepancies through the Bayesian Confidence Propagation Neural Network framework (BCPNN) 29 , while EBGM estimates posterior reporting rates by integrating prior reporting patterns and adjusting for cross-drug variability 27,30