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The vitamin can be stored in the liver for a long time, so it may take a few years for a deficiency to develop ( Summary Vitamin B12 is a water-soluble vitamin that plays an important role in brain function and red blood cell production

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That is a bit of a catch-22 because B12 is essential for the intestines to be able to function optimally, but they cannot absorb it (from the food) when they are damaged or diseased