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SJS AND TEN TEN (formerly known as Lyell syndrome) is a rare severe mucocutaneous reaction that manifests as a maculopapular rash with blistering of skin and conjunctival, oral, and genital mucosae
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Ethanol metabolism, CYP2E1 induction, compromised antioxidant defenses, mitochondrial injury, activation of Kupffer and stellate cells, hypoxia, and iron overload can all contribute to the alcohol-induced oxidative environment
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