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Initial assessment of rats subjected to two ligations at the left colic artery and vein for 15 min, followed by reperfusion for next 15 min (IC + RL rats) Regular course (saline bath, control): After a saline bath was applied to the reperfused colon segment, the arcade vessels were poorly established from proximal to distal arcades

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However, formation of glial scar via the accumulation of reactive astrocytes is a major obstacle to axonal regeneration by neurons after injuries (Zhang and De Koninck, 2006