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Study has revealed that GSH levels in both serum and follicular fluid are significantly lower in PCOS patients versus healthy controls, accompanied by elevated OS markers such as MDA and decreased paraoxonase-1 activity, indicating a decline in the body’s antioxidant defense capacity and an exacerbation of lipid peroxidation (184)

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These observations were supported by a separate study in children, which also found significantly lower plasma concentrations of glycine and glutamate in mild asthmatics than in healthy controls (284)