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In the in vivo experiments, mice were shaved (Back: 2 × 3 cm [2]) on the 50th day from birth and the depilated areas were coated with saline, 5 % minoxidil, CaT containing 2 % copper peptides, and CaT-ME containing 2 % copper peptides daily after shaving, with 6 mice per group

FDA_Fix_DES_REM

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Other considerations documented for tirzepatide in its FDA labeling include injection-site reactions, decreased appetite, and warnings such as the risk of thyroid C-cell tumors observed in rodents (a boxed warning) and pancreatitis and gallbladder events