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In laboratory research, IGF-1 LR3 is used to investigate growth factor–mediated signaling pathways that regulate cellular proliferation, differentiation, metabolism, and protein synthesis

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Results SIRT7 is downregulated in human and murine AAA To identify HDAC family members involved in AAA pathogenesis, we analyzed the expression of all 18 HDAC isoforms in human AAA lesions and paired adjacent abdominal aorta (adjacent AA) tissues